Category 2

Li Ka Shing Prize

Oral exam of Jialing

Graduate Photo of Dicky and Carol

Review article on m6A deregulation in HCC

Our recent review paper on m6A deregulation in liver cancer has been published on-line with open access. This review provides an updated...

CRISPR library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC

Larry's CRISPR/Cas9 library screening study has been published in Nature Communications (Wei et al., Nat Commun 2019l 10:4681). This...

Histone Chaperone FACT complex in oxidative stress response

Jialing’s paper on FACT complex in oxidative stress response has been published in Gut. Big congratulation!! In this study, Jialing...

Super-enhancer landscape in liver cancer

Felice's paper on super-enhancer landscape in liver cancer has been published in Hepatology! In this study, Felice revealed an extensive...

HELLS regulates chromatin remodeling in liver cancer

Dicky's paper has been published in Hepatology! In this study, Dicky revealed that overexpression of HELLS increased nucleosome occupancy...

Deregulation of RNA m6A modification in liver cancer

RNA N6-methyladenosine (m6A) promotes epigenetic silencing of tumor suppressor genes in HCC. Our study on METTL3 deregulation and m6A...

Non-coding RNA in HCC

Our review paper on non-coding RNA and liver cancer is published in Nature Reviews Gastroenterology and Hepatology.

Cancer Genomics and Epigenomics Laboratory